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The functions of micronutrients are so vast that it would be impossible to list them all here

Over time, these combined effects of stress and environmental factors can result in a compromised skin barrier, decreased collagen production, and an overall loss of elasticity, contributing to a less vibrant and youthful appearance

Grasemann L

2 illustrates these effects in humans [8,16]

LRP-1 ablation leads to transcriptional activation of the self-autonomous pathway CypA-MMP9, resulting in increased levels of cyclophilin A (CypA) and matrix-metalloprotease (MMP)-9 as detected by real-time PCR and immunohistochemistry [111]